产品货号:
Z33334
中文名称:
BACE1抗体
英文名称:
Anti-BACE1 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-BACE1 Antibody |
指标别名 | Asp 2;ASP2;Aspartyl protease 2;BACE;BACE1;Beta secretase 1;HSPC104;KIAA1149;Memapsin 2 |
克隆性 | Monoclonal |
检验物种 | human,mouse,rat |
应用范围 | WB |
基因名称 | BACE1 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | A synthesized peptide derived from human BACE1 |
实际分子量 | 70KD |
成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
纯化方式 | Affinity-chromatography |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | beta-secretase,encoded by BACE1(beta-stie amyloid beta A4 precursor protein-cleavage enzyem1) gene,is a neuron-specific membrane-associated protease that participate in the two step proteolytic processing of the APP.Cleaves at the N-terminus of the A-beta peptide sequence,between residues 671 and 672 of APP,leads to the generation and extracellular release of beta-cleaved soluble APP,and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.It has a high expression in the brain and pancreas.This protein has 6 isoforms produced by alternative splicing.BACE1 can be detected with different molecular weight:42~56kD (prozymogen and isoforms),65-75 (glycosylated forms) and 160kDa (dimer) (PMID:22741101;21795680). |
Uniprot ID | P56817 |
推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot.*Blocking peptide可以联系我们购买。 |
基因名全称 | Beta-secretase 1 |
推荐稀释比 | Western blot (WB) 1:500~2000 |
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